p21(Cip1) plays acritical role in the physiological adaptation to fasting through activation of PPARα.
Lopez-Guadamillas E, Fernandez-Marcos PJ, Pantoja C, Muñoz-Martin M, Martínez D, Gómez-López G, Campos-Olivas R, Valverde AM, Serrano M.
Sci Rep. 2016 Oct 10;6:34542.
PMID: 27721423
Pax8 controls thyroid follicular polarity through Cadherin-16.
Koumarianou P, Goméz-López G, Santisteban P.
J Cell Sci. 2016 Oct 25.
PMID: 27780871
Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5.
García-Fernández M, Karras P, Checinska A, Cañón E, Calvo GT, Gómez-López G, Cifdaloz M, Colmenar A, Espinosa-Hevia L, Olmeda D, Soengas MS.
Autophagy. 2016 Oct 2;12(10):1776-1790.
PMID: 27464255
NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation.
García-Carpizo V, Sarmentero J, Han B, Graña O, Ruiz-Llorente S, Pisano DG, Serrano M, Brooks HB, Campbell RM, Barrero MJ.
Sci Rep. 2016 Sep 8;6:32952.
PMID: 27604143
Multilayer OMIC data in medullary thyroid carcinoma identifies the STAT3 pathway as a potential therapeutic target in RETM918T tumors.
Mancikova V, Montero-Conde C, Perales-Paton J, Fernandez AF, Santacana M, Jodkowska K, Inglada-Pérez L, Castelblanco E, Borrego S, Encinas M, Matias-Guiu X, Fraga MF, Robledo M.
Clin Cancer Res. 2016 Sep 12.
PMID: 27620278
A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance.
Martínez P, Gómez-López G, Pisano DG, Flores JM, Blasco MA.
Aging Cell. 2016 Sep
PMID: 27586969
Telomeric RNAs are essential to maintain telomeres.
Montero JJ, López de Silanes I, Graña O, Blasco MA.
Nat Commun. 2016 Aug 17;7:12534.
PMID: 27531349
Targeted sequencing reveals low-frequency variants in EPHA genes as markers of paclitaxel-induced peripheral neuropathy.
Apellániz-Ruiz M, Tejero H, Inglada-Pérez L, Sánchez-Barroso L, Gutiérrez-Gutiérrez G, Calvo I, Castelo B, Redondo A, García-Donás J, Romero-Laorden N, Sereno M, Merino M, Currás-Freixes M, Montero-Conde C, Mancikova V, Åvall-Lundqvist E, Green H, Al-Shahrour F, Cascon A, Robledo M, Rodriguez-Antona C.
Clin Cancer Res. 2016 Aug 31.
PMID: 27582484
Deep sequencing reveals microRNAs predictive of antiangiogenic drug response.
García-Donas J, Beuselinck B, Inglada-Pérez L, Graña O, Schöffski P, Wozniak A, Bechter O, Apellániz-Ruiz M, Leandro-García LJ, Esteban E, Castellano DE, González Del Alba A, Climent MA, Hernando S, Arranz JA, Morente M, Pisano DG, Robledo M, Rodriguez-Antona C.
JCI Insight. 2016 Jul 7;1(10):e86051.
PMID: 27699216
Targeting Tumor Mitochondrial Metabolism Overcomes Resistance to Antiangiogenics.
Navarro P, Bueno MJ, Zagorac I, Mondejar T, Sanchez J, Mourón S, Muñoz J, Gómez-López G, Jimenez-Renard V, Mulero F, Chandel NS, Quintela-Fandino M.
Cell Rep. 2016 Jun 21;15(12):2705-18.
PMID: 27292634
Analysis of Paired Primary-Metastatic Hormone-Receptor Positive Breast Tumors (HRPBC) Uncovers Potential Novel Drivers of Hormonal Resistance.
Manso L, Mourón S, Tress M, Gómez-López G, Morente M, Ciruelos E, Rubio-Camarillo M, Rodriguez-Peralto JL, Pujana MA, Pisano DG, Quintela-Fandino M.
PLoS One. 2016 May 19;11(5):e0155840.
PMID: 27195705
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.
Puram RV, Kowalczyk MS, de Boer CG, Schneider RK, Miller PG, McConkey M, Tothova Z, Tejero H, Heckl D, Järås M, Chen MC, Li H, Tamayo A, Cowley GS, Rozenblatt-Rosen O, Al-Shahrour F, Regev A, Ebert BL.
Cell. 2016 Apr 7;165(2):303-16.
PMID: 27058663
Vitamin D receptor expression and associated gene signature in tumour stromal fibroblasts predict clinical outcome in colorectal cancer.
Ferrer-Mayorga G, Gómez-López G, Barbáchano A, Fernández-Barral A, Peña C, Pisano DG, Cantero R, Rojo F, Muñoz A, Larriba MJ.
Gut. 2016 Apr 6.
PMID: 27053631
Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation.
Elf S, Abdelfattah NS, Chen E, Perales-Patón J, Rosen EA, Ko A, Peisker F, Florescu N, Giannini S, Wolach O, Morgan EA, Tothova Z, Losman JA, Schneider RK, Al-Shahrour F, Mullally A.
Cancer Discov. 2016 Apr;6(4):368-81.
PMID: 26951227
Chronic skin inflammation leads to bone loss by IL-17-mediated inhibition of Wnt signaling in osteoblasts.
Uluçkan Ö, Jimenez M, Karbach S, Jeschke A, Graña O, Keller J, Busse B, Croxford AL, Finzel S, Koenders M, van den Berg W, Schinke T, Amling M, Waisman A, Schett G, Wagner EF.
Sci Transl Med. 2016 Mar 16;8(330):330ra37.
PMID: 27089206
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma.
Ambrogio C, Gómez-López G, Falcone M, Vidal A, Nadal E, Crosetto N, Blasco RB, Fernández-Marcos PJ, Sánchez-Céspedes M, Ren X, Wang Z, Ding K, Hidalgo M, Serrano M, Villanueva A, Santamaría D, Barbacid M.
Nat Med. 2016 Mar;22(3):270-7.
PMID: 26855149
