2024

The 1+Million Genomes Minimal Dataset for Cancer

Riba M, Sala C, Culhane AC, Flobak Å, Patocs A, Boye K, Plevova K, Pospíšilová Š, Gandolfi G, Morelli MJ, Bucci G, Edsjö A, Lassen U, Al-Shahrour F, Lopez-Bigas N, Hovland R, Cuppen E, Valencia A, Poirel HA, Rosenquist R, Scollen S, Arenas Marquez J, Belien J, De Nicolo A, De Maria R, Torrents D, Tonon G.
Nat Genet. 2024 May;56(5):733-736. doi: 10.1038/s41588-024-01721-x.
PMID: 38702538

The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells

López-Gil JC, García-Silva S, Ruiz-Cañas L, Navarro D, Palencia-Campos A, Giráldez-Trujillo A, Earl J, Dorado J, Gómez-López G, Monfort-Vengut A, Alcalá S, Gaida MM, García-Mulero S, Cabezas-Sáinz P, Batres-Ramos S, Barreto E, Sánchez-Tomero P, Vallespinós M, Ambler L, Lin ML, Aicher A, García García de Paredes A, de la Pinta C, Sanjuanbenito A, Ruz-Caracuel I, Rodríguez-Garrote M, Guerra C, Carrato A, de Cárcer G, Sánchez L, Nombela-Arrieta C, Espinet E, Sanchez-Arevalo Lobo VJ, Heeschen C, Sainz B Jr.
Gut. 2024 May 16. doi: 10.1136/gutjnl-2023-330995. Epub ahead of print.
PMID: 38754953

Hepatic nutrient and hormone signaling to mTORC1 instructs the postnatal metabolic zonation of the liver

Plata-Gómez AB, de Prado-Rivas L, Sanz A, Deleyto-Seldas N, García F, de la Calle Arregui C, Silva C, Caleiras E, Graña-Castro O, Piñeiro-Yáñez E, Krebs J, Leiva-Vega L, Muñoz J, Jain A, Sabio G, Efeyan A.
Nat Commun. 2024 Mar 18;15(1):1878. doi: 10.1038/s41467-024-46032-1.
PMID: 38499523

The T2T-CHM13 reference assembly uncovers essential WASH1 and GPRIN2 paralogues

Cerdán-Vélez D, Tress ML.
Bioinform Adv. 2024 Feb 28. doi: 10.1093/bioadv/vbae029
PMID: 38464973

A community challenge to predict clinical outcomes after immune checkpoint blockade in non-small cell lung cancer

Mason M, Lapuente-Santana Ó, Halkola AS, Wang W, Mall R, Xiao X, Kaufman J, Fu J, Pfeil J, Banerjee J, Chung V, Chang H, Chasalow SD, Lin HY, Chai R, Yu T, Finotello F, Mirtti T, Mäyränpää MI, Bao J, Verschuren EW, Ahmed EI, Ceccarelli M, Miller LD, Monaco G, Hendrickx WRL, Sherif S, Yang L, Tang M, Gu SS, Zhang W, Zhang Y, Zeng Z, Das Sahu A, Liu Y, Yang W, Bedognetti D, Tang J, Eduati F, Laajala TD, Geese WJ, Guinney J, Szustakowski JD, Vincent BG, Carbone DP.
J Transl Med. 2024 Feb 21. doi: 10.1186/s12967-023-04705-3
PMID: 38383458

Roadmap for a European cancer data management and precision medicine infrastructure

Nikolski M, Hovig E, Al-Shahrour F, Blomberg N, Scollen S, Valencia A, Saunders G.
Nat Cancer. 2024 Feb 6. doi: 10.1038/s43018-023-00717-6
PMID: 38321342

The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2

Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M.
Nat Cancer. 2024 Jan 24. doi: 10.1038/s43018-023-00712-x
PMID: 38267628